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The Kirby Institute

The Kirby Institute is a major research organisation in Australia conducting research into the clinical and epidemiological aspects of blood-borne virus infections, including hepatitis C and HIV. The research has a particular focus on marginalised populations, including people who inject drugs and prisoners.

For further information see: kirby.unsw.edu.au

 

Organisational partners

The SToP-C study was a partnership project led by The Kirby Institute, UNSW Sydney, in collaboration with the following organisations:

 

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  • SToP-C Investigators
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    • Andrew Lloyd

        Professor Andrew Lloyd was co-chief investigator of the SToP-C project. He is an infectious diseases physician, and an epidemiology, virology and immunology researcher. He is the Head of the Viral Immunology Systems Program (VISP) in the Kirby Institute, UNSW Sydney. He also provides clinical services in infectious diseases at Prince of Wales Hospital, Sydney and hepatology services to Justice Health in the New South Wales prisons.

    • Gregory Dore

        Professor Gregory Dore was co-chief investigator of the SToP-C project. He is a clinical epidemiologist and Head of the Viral Hepatitis Clinical Research Program in the Kirby Institute, UNSW Sydney, and an infectious diseases physician at St Vincent’s Hospital, Sydney, Australia, and the Parklea Correctional Centre.

    • Jason Grebely

        Professor Jason Grebely is a clinical epidemiologist in the Viral Hepatitis Clinical Research Program at the Kirby Institute, UNSW Sydney. His research activities are mainly focused on the epidemiology and natural history of hepatitis C virus infection, strategies for enhancing assessment and treatment of hepatitis C virus infection in people who use drugs, and other harms that may occur from drug use.

    • Carla Treloar

        Professor Carla Treloar was the senior investigator for the SToP-C qualitative research component. Carla is Director of the Centre for Social Research in Health and the Social Policy Research Centre at UNSW Sydney. She is a primarily qualitative researcher and is grounded in the disciplines of health and social psychology, public health and health policy. Her research focus is in the fields of hepatitis C and injecting drug use.

    • Georgina Chambers

        Associate Professor Georgina Chambers led the SToP-C health economic evaluation. Georgina is the Director of the National Perinatal Epidemiology and Statistics Unit, UNSW Sydney. She has research experience in the Australian public and private healthcare sectors in public health research, health economics, medical science and health services management.

    • Natasha Martin

        Associate Professor Natasha Martin was co-lead investigator on the SToP-C mathematical modelling. Natasha is an infectious disease economic modeler who develops dynamic transmission models to evaluate the impact and cost-effectiveness of public health interventions. She is an Associate Professor in the Division of Global Public Health, Department of Medicine at the University of San Diego and holds an honorary senior lecturer position in the School of Social and Community Medicine, University of Bristol.

    • Peter Vickerman

        Professor Peter Vickerman was co-lead investigator on the SToP-C mathematical modelling. Peter is a Professor in infectious disease modelling at the University of Bristol and has an honorary position at the London School of Hygiene and Tropical Medicine. His research focuses on the use of mathematical modelling to help understand the transmission of different infectious diseases and impact and cost-effectiveness of prevention measures.

  • Other SToP-C Researchers
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    • Behzad Hajarizadeh

        Dr Behzad Hajarizadeh led the primary analysis of the SToP-C project. Behzad is a clinical epidemiologist in the Viral Hepatitis Clinical Research Program at the Kirby Institute, UNSW Sydney. His research is focused on the epidemiology and natural history of acute and chronic hepatitis C infection and re-infection; hepatitis C management and barriers to care in the prison setting and among people who inject drugs.

    • Janaki Amin

        Professor Janaki Amin was the SToP-C study statistician. Janaki is an epidemiologist and biostatistician. Her primary activities and interests include design and analysis of clinical trials and data linkage studies, and analysis of cohort studies. A significant body of her expertise has arisen from data linkage studies of cancer and mortality among people notified with hepatitis B or C.

    • Lise Lafferty

        Dr Lise Lafferty led the qualitative research work related to prisoner and prison staff perspectives. Lise is co-appointed to the Centre for Social Research in Health on a number of studies pertaining to people living with BBVs, people who inject drugs, and people in prison; and at the Kirby Institute on a study promoting point-of-care sexual health testing in Aboriginal communities.

    • Jake Rance

        Dr Jake Rance led the qualitative research work related to policymaker perspectives. Jake works at the Centre for Social Research in Health (CSRH) and has worked for many years in harm reduction services. He has a disciplinary background in philosophy, politics and cultural studies.

    • Marianne Byrne

        Marianne Byrne coordinated the SToP-C project. Marianne is a Clinical Trials Manager with qualifications in public health, project management and clinical trials management. She works across both the Kirby Institute and National Drug and Alcohol Research Centre at University of New South Wales.

  • SToP-C Nurses

      Angela Smith
      Ronella Williams
      Brigid Cooper
      Camilla Lobo
      Carina Burns
      Kelly Somes
      Karen Conroy
      Anoop Kaur

  • SToP-C Dedicated Correctional Officers

      Carolyn Cafe
      Jodie Anlezark

  • Implementation Committee

      The Implementation Committee is a sub-committee of the SToP-C Protocol Steering Committee. Throughout the duration of the project, the Implementation Sub-Committee advised on and contributed to the development of the implementation plan and this toolkit. Key aspects included: development of processes for collection of key information to inform the toolkit; documentation of barriers, obstacles and solutions throughout all phases of the project; assessment of key scalability considerations; and integration with policy.

       

      Andrew Lloyd (Chair)
      Viral Immunology Systems Program, Kirby Institute UNSW Sydney.

      Jason Grebely
      Viral Hepatitis Clinical Research Program, Kirby Institute UNSW Sydney.

      Colette McGrath
      Population Health Service, Justice Health and Forensic Mental Health Network

      Andrew Milat
      Centre for Epidemiology and Evidence, NSW Health

      Julia Bowman
      Research Unit, Justice Health and Forensic Mental Health Network

      Katerina Lagios
      Justice Health and Forensic Mental Health Network

      Libby Topp
      Centre for Population Health, NSW Health

      Ivan Calder
      Corrective Services NSW

      Marianne Byrne
      Viral Hepatitis Clinical Research Program, Kirby Institute, UNSW Sydney

       

      The draft Implementation Toolkit was also reviewed and received input from the following external reviewers, involved in hepatitis C care and service delivery in prisons both in Australia and internationally:

      Matthew Akiyama

      Joaquin Cabezas

      Nadine Kronfli

      Josiah Rich

      Mark Stoove

      Alexander Thompson

      Karla Thornton

  • Qualitative research investigators

      The social researchers developed and conducted qualitative research interviews throughout the project with key stakeholders, to assess the acceptability of the intervention, prisoner and provider attitudes and perceived barriers, and perceptions of what should constitute a program of HCV prevention in correctional centres beyond the treatment as prevention paradigm.

      Participant interviews included prisoners, correctional staff, prison health staff, senior bureaucrats in health and correctional authorities, expert stakeholders, and policy makers.

       

      Carla Treloar
      Centre for Social Research in Health, UNSW Sydney

      Lise Lafferty
      Centre for Social Research in Health, UNSW Sydney

      Jake Rance
      Centre for Social Research in Health, UNSW Sydney

  • Mathematical modelling investigators

      Mathematical modelling was performed during the study using SToP-C year 1 surveillance data to model the number of prisoners required to be treated to demonstrate a significant reduction in incidence. The modelling performed after study completion included the contribution of Stop C prison treatment to observed declines in HCV incidence in the STOP-C study, the potential impact of prison-based interventions on HCV transmission among PWID and their importance for HCV elimination.

       

      Natasha Martin
      Division of Infectious Diseases and Global Public Health, University of California San Diego

      Peter Vickerman
      Bristol Medical School, Bristol University

      Jack Stone
      Bristol Medical School, Bristol University

  • Health economics investigators

      The cost-effectiveness of scaling up HCV treatment as prevention and budget impact was evaluated in the context of the NSW prison system.

       

      Georgina Chambers
      National Perinatal Epidemiology and Statistics Unit, UNSW Sydney

  • Protocol Steering Committee members

      The SToP-C project was guided by a Project Steering Committee which will include the chief investigators of the project and representatives from Justice Health and Forensic Mental Health Network, the Department of Corrective Services, NSW Health and consumer organisations (Hepatitis NSW, NSW Users & AIDS Association, and Community Restorative Centre).

       

      Stuart Loveday (Chair)
      Hepatitis NSW

      Steven Drew
      Hepatitis NSW

      Greg Dore
      Viral Hepatitis Clinical Research Program, Kirby Institute UNSW Sydney

      Andrew Lloyd
      Viral Immunology Systems Program, Kirby Institute UNSW Sydney

      Jason Grebely
      Viral Hepatitis Clinical Research Program, Kirby Institute UNSW Sydney

      Carla Treloar
      Centre for Social Research in Health, UNSW Sydney

      Luke Grant
      Strategy and Policy, Corrective Services NSW

      Terry Murrell
      Custodial Operations, Corrective Services NSW

      Colette McGrath
      Population Health Service, Justice Health and Forensic Mental Health Network

      Julia Bowman
      Research Unit, Justice Health and Forensic Mental Health Network

      Lee Trevethan
      Justice Health and Forensic Mental Health Network

      Katerina Lagios
      Justice Health and Forensic Mental Health Network

      Roy Donelly
      Justice Health and Forensic Mental Health Network

      Belinda Martin
      Centre for Population Health, NSW Health

      Annabelle Stevens
      Centre for Population Health, NSW Health

      Victor Tawil
      Centre for Population Health, NSW Health

      Libby Topp
      Centre for Population Health, NSW Health

      Alison Churchill
      Community Restorative Centre

      Kate Pinnock
      Community Restorative Centre

      Mary Harrod
      NSW Users and AIDS Association

      Charles Henderson
      NSW Users and AIDS Association

      Nicky Bath
      NSW Users and AIDS Association

      Marianne Byrne
      Viral Hepatitis Clinical Research Program, Kirby Institute, UNSW Sydney

  • Education Resources Committee members

      The Education Resources Committee is a sub-committee of the Protocol Steering Committee. It acted in an advisory capacity to guide the development and evaluation of resources. A creative agency, Utility Creative, was contracted to for the aesthetic, branding, design, and creation of materials.

       

      Andrew Lloyd
      Viral Immunology Systems Program, Kirby Institute UNSW Sydney

      Jason Grebely
      Viral Hepatitis Clinical Research Program, Kirby Institute UNSW Sydney

      Kate Pinnock
      Community Restorative Centre

      Jennifer Douglas
      Population Health Service, Justice Health and Forensic Mental Health Network

      Carla Treloar
      Centre for Social Research in Health, UNSW Sydney

      Mary Ellen Harrod
      NSW Users and AIDS Association

      Daniel Potenza
      Utility Creative

      Marianne Byrne
      Viral Hepatitis Clinical Research Program, Kirby Institute, UNSW Sydney

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